Advanced Sulforaphane Protection, Powered by Science
Unlock your body’s natural detox and immune support with clinically validated sulforaphane production. Avmacol Extra Strength delivers a precision-engineered blend that activates powerful antioxidant pathways — all in one daily vegetarian tablet.
Science-Backed Quality You Can Trust
Every one of our supplements goes through up to 80 quality checks and is supported by scientific research, so you can be confident in its safety and effectiveness. We source premium ingredients and manufacture in state-of-the-art facilities, upholding rigorous standards at every step—from raw material to finished bottle.
What is Avmacol® Extra Strength?
Avmacol® Extra Strength is a patented, sulforaphane-producing supplement that works together with Maitake mushroom extract (a source of beta-glucans) to support your body’s natural detoxification processes, more effectively than sulforaphane alone.
Avmacol® Extra Strength provides glucoraphanin (also known as sulforaphane glucosinolate) and an active myrosinase enzyme—two essential components needed for sulforaphane production. Without an active myrosinase enzyme, the body may not be able to fully realize sulforaphane’s many health-promoting benefits.
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Vegetarian
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Gluten-Free
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No Generic Equivalent
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Packaged in BPA-free bottles
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Subject to more than 80 quality checks
Patented, shelf-stable, and tableted formula
Contains glucoraphanin + active myrosinase enzyme
Supports immune health with added beta-glucan
Combination of ingredients works better than sulforaphane alone
From Broccoli to Biochemistry: How Sulforaphane Supports Your Body
Sulforaphane is a result of two specific compounds:
Glucoraphanin, found in broccoli seed and sprout extract
Glucoraphanin, found in broccoli seed and sprout extract
What is Glucoraphanin?
Glucoraphanin, also known as sulforaphane glucosinolate, is a compound that is present in many cruciferous vegetables, most notably in broccoli. It is an essential ingredient needed for sulforaphane production because it is sulforaphane’s direct precursor. The glucoraphanin is converted into sulforaphane after it is processed by an active myrosinase enzyme.
What is Myrosinase?
Myrosinase is an important enzyme required to convert glucoraphanin into sulforaphane. Additionally, it can be found in cruciferous vegetables, though it can become inactivated during the cooking process.
The Science Behind Avmacol®Extra Strength
The combination of sulforaphane and Maitake extract supports the movement (or translocation) from the cytoplasm to the nucleus of NRF2 and increases the levels of certain Phase 2 enzymes. Below are images of a technique called immunofluorescence which illustrate how much protein is being produced in the cell and the location of that protein.
Translocation of NRF2 into the Nucleus Following Exposure to Sulforaphane and Maitake Mushroom Extract
In control cells (left panel), the green staining indicates that NRF2 remains largely in the cytoplasm (arrows) without much protein located in the nucleus, which is counter-stained in blue. When cells are exposed to sulforaphane and Maitake (right panel), NRF2 moves to the nucleus (arrows) where it can bind to DNA to turn on expression of certain Phase 2 enzymes.
Sulforaphane and Maitake Extract Boosts Select Phase 2 Enzyme Production Including NQO1 and HO-1
Validated in Real Human Studies
Our exclusive Sulforaphane Production System® is verified in humans by measuring sulforaphane metabolites in urine, confirming that our formula reliably produces active sulforaphane in the body.
The Choice of Researchers Worldwide
Thanks to Avmacol’s exclusive Sulforaphane Production System®, our formula has been selected for numerous clinical studies around the world, making it a trusted option for researchers and healthcare professionals alike.
Supports Your Body’s Natural Detox Pathways
Sulforaphane helps activate your body’s own detoxification processes to deal with certain environmental toxins and everyday exposures.
Who Can Benefit from Avmacol® Extra Strength?
We are capable of incredible things; and when our bodies get the support they need, the results can be amazing. Avmacol® unleashes the power of broccoli to help your body fight off toxin-related stress at the cellular level.
FAQs
Why does Avmacol include both glucoraphanin and active myrosinase?
Why does Avmacol include both glucoraphanin and active myrosinase?
Because glucoraphanin alone does not convert into active sulforaphane without myrosinase. Avmacol’s formula ensures your body can effectively produce sulforaphane and benefit from its effects.
Can one tablet a day really provide sufficient support?
Can one tablet a day really provide sufficient support?
Yes — just one convenient tablet per day provides the combined precursors and enzyme needed for sulforaphane production, plus immune support via maitake extract.
Is Avmacol Extra Strength backed by research?
Is Avmacol Extra Strength backed by research?
Yes — Avmacol is widely used in human clinical studies thanks to its validated Sulforaphane Production System®, making it one of the most researched sulforaphane supplements.
Are there any artificial colors, gluten, or animal-derived ingredients in Avmacol Extra Strength?
Are there any artificial colors, gluten, or animal-derived ingredients in Avmacol Extra Strength?
No — Avmacol Extra Strength contains no artificial colors, and excludes gluten. It is formulated to be vegetarian-friendly.